Track-and-trace method predicts best possible resolution in microscopy

TU Delft scientists provide insight into the limitations of super-resolution microscopy and offer a new calculation method to determine maximum resolution. The major precision improvements previously claimed by fellow-researchers are nuanced by their publication. The technology is important for studying processes in the living cell, discovering the origin of diseases and developing new medicines. Their findings were published in Biophysical Journal . Delft research. In 2019, researchers from Delft had already given the field of super-resolution microscopy a considerable boost by improving the precision of the technique about twofold ( see here ). Now they have published a scientific article that points out the fundamental limitations of super-resolution microscopy.